Vegas oddsmakers are expecting a competitive upcoming slate, as the Week 5 NFL odds have all matchups with NFL spreads under 10 points. The Dolphins are 9.5-point home favorites over the Giants, while the Lions are 8.5-point favorites at home versus the winless Panthers in the latest NFL betting lines. Carolina is one of a handful of teams yet to cover the spread this season, which could be a trend to consider for your Week 5 NFL bets. Meanwhile, Detroit is tied with an NFL-high three wins against the spread this season.

The NFL betting trends for this matchup clearly favorite the Lions in a matchup of top overall picks Jared Goff and Bryce Young. Should your Week 5 NFL picks align with the NFL betting trends, or could this be the latest surprise result in a season that has already seen lots of them? All of the Week 5 NFL lines are listed below, and SportsLine’s advanced computer model has all the NFL betting advice and predictions you need to make the best Week 5 NFL picks now.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 5 of the 2023 NFL season on an incredible 168-118 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 22-10 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, it has turned its attention to the latest Week 5 NFL odds and locked in picks for every NFL matchup. Head here to see every pick.

Top Week 5 NFL predictions
One of the model’s strongest Week 5 NFL picks is that the Eagles (-4.5) cover against the Rams. These teams are next to each other in defensive rankings, as Los Angeles ranks 15th in scoring defense, while Philadelphia ranks 16th. The difference between the two lies on the offensive end, where the Eagles are top-five in points per game, while the Rams are a middling 13th.

Behind Matthew Stafford’s arm, the Rams lead the NFL in pass attempts and rank second in passing yards. However, that high volume hasn’t lent itself to efficiency where it matters the most since just two teams have fewer passing touchdowns than L.A. That inefficient offense is paired with a defense that doesn’t generate extra possessions. The Rams have the second-fewest takeaways in the league with two, while the Eagles have forced eight turnovers in 2023. With the gaps in between the two on offense and in turnover differential, the model has Philadelphia covering in well over 50% of simulations. See which other teams to pick here.

Another one of its Week 5 NFL predictions: The Patriots (-1.5) cover the spread at home versus the Saints. Mac Jones and Derek Carr have underperformed this year, but at least Jones doesn’t have more turnovers than touchdowns, unlike Carr. The former Raider hasn’t thrown more than one touchdown in each of his last five starts and is dealing with a shoulder injury that’s held him under 130 passing yards in each of his last two starts. He’s also been a sitting duck in the pocket and has been sacked the fifth-most times despite ranking 20th in dropbacks.

New England fields one of just three units that ranks in the top 10 against the run and pass. With Carr and the Saints’ passing offense already shooting itself in the foot, the Patriots can load up against New Orleans’ run game, which has its own struggles. The team ranks in the bottom 10 in both rushing yards and yards per carry, while New Orleans finished with just 70 yards on the ground in Alvin Kamara’s Week 4 return. Add in the fact that the Saints have not covered in a single game this season and New England (-1.5) is projected to cover well over 50% of the time. The model also says the Under (39) hits in well over 50% of simulations. See which other teams to pick here.

eno Smith voiced his frustration with the New York Giants after leaving Monday’s game midway in the second quarter with a knee injury. Smith returned to the game and rallied the Seattle Seahawks to a 24-3 victory, but still wasn’t pleased with how the injury occurred to his knee — and how he had to leave the MetLife Stadium field on the cart.

“A dirty play. Dirty play,” Smith told ESPN after the game. “You guys can see it. It was a dirty play. It’s no place in this sport for that and hopefully something happens, but other than that, the grace of God allowed me to come back into this game and I’m happy to be back out there.”

Geno Smith showed his frustration after Isaiah Simmons tackled him on the sideline 😳#SEAvsNYG pic.twitter.com/d0trgckmkc

— ESPN (@espn) October 3, 2023
Smith walked up to Giants safety Xavier McKinney after the play and voiced his displeasure with him. He ended up playing one more snap before missing the next two series with the knee injury. He returned to the game in time for the start of the second half, and even got a 15-yard penalty for taunting the Giants in the third quarter.

“I just don’t respect that type of stuff,” Smith said. “There’s no need for that type of stuff. It’s a hard-fought game out there. We’re all battling, but there’s no need to take shots at guys running out of bounds on the sideline.”

Smith had a slight limp due to the knee, but said he was fine. The Seahawks have a bye week coming up, so Smith gets a week to rest up the knee. While Smith wasn’t happy with the play, Isaiah Simmons defended the tackle — which was initially started in bounds after Smith caught his own pass in the backfield and tried to make something happen.

“We playing football. He’s mad he got hit? What do most quarterbacks do when they don’t want to get hit? They go down,” Simmons said. “I don’t really know what else to tell him about that.”

The New England Patriots suffered their worst loss of the 2023 season on Sunday, as they were trounced by the Dallas Cowboys, 38-3. Unfortunately, the losses didn’t stop there for the Patriots, as New England lost two of its most important defenders in cornerback Christian Gonzalez and pass rusher Matt Judon to injuries.

Gonzalez suffered a shoulder injury while Judon suffered a torn biceps. Both players will reportedly be out indefinitely, and Judon will undergo surgery this Wednesday, per ESPN. Judon reportedly wants to return this season, but it’s unknown if he will be able to. That all depends on how his recovery goes.

Patriots Pro Bowl edge Matthew Judon suffers and injury late in the game against the #Cowboys. pic.twitter.com/15pClj401t

— Pro Football Network (@PFN365) October 1, 2023
In four games, the 31-year-old Judon recorded 13 combined tackles, four sacks and nine QB hits. In 2022, Judon recorded a career-high 15.5 sacks and 28 QB hits to go along with 60 combined tackles. He has made four straight Pro Bowls — a streak that will be snapped this season.

This is a monster loss for the Patriots, as Judon is not only the best player on New England’s defense, but the unit’s leader as well. In his absence, Josh Uche and Anfernee Jennings are two players who could receive promotions. Bill Belichick could also look toward second-round pick Keion White, who hasn’t played more than 39% of defensive snaps in any of New England’s four games this season.

There are not any double-digit favorites in the latest Week 5 NFL odds from the SportsLine Consensus, creating plenty of difficult decisions for your NFL bets. Baltimore is a 4.5-point favorite against Pittsburgh in the Week 5 NFL spreads as its three-game road trip continues. The Ravens opened the trip with a 28-3 win at Cleveland last week, while the Steelers are coming off a 30-6 loss at Houston. Should you include Baltimore covering the spread in your Week 5 NFL predictions?

Other important games on the Week 5 NFL schedule include the Rams (+4.5) vs. Eagles, Chiefs (-5.5) vs. Vikings and 49ers (-3.5) vs. Cowboys. Which Week 5 NFL spreads have the most value? Before you make any Week 5 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 5 of the 2023 NFL season on an incredible 168-118 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 22-10 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in five confident NFL best bets for Week 5. If you successfully parlay its picks, you’d be looking at a massive payout of around 25-1. You can only see the model’s Week 5 NFL picks at SportsLine.

Top Week 5 NFL picks
After simulating every game 10,000 times, the model is high on the Kansas City Chiefs (-5.5) to cover on the road against the Minnesota Vikings. Kansas City raced out to a 17-0 lead in New York last Sunday before having to escape in a 23-20 win over the Jets. The Chiefs racked up more than 400 total yards in the victory, extending their winning streak to three games.

Star quarterback Patrick Mahomes has already gone over 1,000 passing yards on the season, tossing eight touchdowns. Minnesota is coming off its first win of the season, squeaking past the Panthers in a matchup of 0-3 teams. The Vikings have already lost to the Buccaneers and Chargers at home, allowing a combined 48 points in those setbacks.

SportsLine’s model believes Mahomes will rack up nearly 350 total yards on Sunday, with tight end Travis Kelce coming close to 100 receiving yards in a performance we know all too well. That is a big reason why the Chiefs are covering the spread in 60% of simulations. See which other NFL parlay picks to make here.

In the third quarter, he made a defender miss on a nifty scramble but did take a big hit short of the first-down marker.
On a 3rd-and-11 in the third quarter, Young bounced around in the pocket and found his target for a first down, throwing an accurate ball while on the move and a defender closing in.
Late in the game, Young somehow slipped out of a would-be sack and did enough to pick up a first down on 3rd and 4.
Low-Caliber Throws/Plays:

On the first play of the second quarter, he attempted a bubble screen and should’ve been intercepted by a Vikings defensive lineman.
While trying to evade an outside rusher in the third quarter, Young had a costly fumble.
On the last offensive play for the Panthers, Young took a sack. Can’t do that. He has to get the ball out of his hands to give one of his receivers a chance to make a play on the football.
Summary: This was reminiscent of a rookie year Mac Jones or an early-career Jalen Hurts game. Essentially no difficult asks throw-wise. Young wasn’t protected well all contest but did hold onto the ball for a long time often and outside of a few creative scampers, was unable to evade pressure and generate big plays outside of structure.

The Carolina Panthers remain the gift that keeps on giving when it comes to NFL survivor pool picks. They remain winless and just gave the Vikings their first victory ahead of a trip to Detroit on Sunday. Dan Campbell is making believers out of even the biggest Lions’ pessimists and Detroit appears to be one of the top options for Week 5 NFL knockout pool picks. The Panthers beat the Lions in Week 16 of last season, running for a franchise-record 320 yards. While that could serve as a source of motivation for Detroit on Sunday, it could serve as a blueprint for Carolina to upend many NFL pool picks. Before finalizing any Week 5 NFL survivor picks, see which team the red-hot SportsLine Projection Model just went all-in on.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 5 of the 2023 NFL season on an incredible 168-118 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 22-10 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, it has turned its attention to the latest Week 5 NFL odds and locked in its Week 5 survivor pool pick. You can only see who the model is backing this week at SportsLine.

Top Week 5 NFL survivor pool predictions
For Week 5 of the 2023 NFL season, the model is shying away from the Ravens, even though they are 4.5-point favorites over the Steelers. Pittsburgh is 5-1 against Baltimore over the last six meetings and the Steelers have gotten the better of Lamar Jackson in their matchups. Pittsburgh is one of three NFL teams in which Jackson has a losing record against, in addition to Kansas City and Miami. The quarterback has twice as many turnovers (eight) as passing plus rushing touchdowns (four) in his career against the rival Steelers.

While Kenny Pickett’s (knee) status is yet to be decided, the Steelers potentially going to backup Mitch Trubisky doesn’t mean an easy victory, or any victory, for Baltimore. Two weeks ago, backup Gardner Minshew filled in for Colts starter Anthony Richardson and upset the Ravens in Baltimore. Now, the Ravens have to travel to Pittsburgh, and the team has several injury concerns as well. Baltimore had six starters sidelined last Sunday, so the model advises to bypass it with Week 5 NFL knockout picks and save the Ravens for later in the year. See which team to pick here.

New York Jets head coach Robert Saleh has been telling anyone who would listen since future Hall of Fame quarterback Aaron Rodgers went down with a torn Achilles that Zach Wilson is their guy despite him making the unfortunate history of being the only player since the 1970 AFL-NFL merger to rank dead last in passer rating in consecutive seasons (69.7 in 2021 and 72.8 in 2022). Saleh and general manager Joe Douglas need him to look somewhat competent in this season-long addition since they went all in on selecting him second overall in the 2021 NFL Draft.

Wilson checked the competent box in Week 4, totaling 245 passing yards, two touchdowns and no interceptions on 28 of 39 passing for a 105.2 passer rating in a 23-20 loss against the defending Super Bowl champion Kansas City Chiefs on “Sunday Night Football.” Sunday night marked the first game of Wilson’s career in which he had multiple passing touchdowns and no interceptions in a game. His opponent, Patrick Mahomes — the reigning NFL and Super Bowl MVP — threw for 203 passing yards while also accumulating a touchdown and two interceptions on 18 of 30 passing for a 63.6 passer rating. Those statistics led to Wilson being the first quarterback to have more completions, more passing yards, more passing touchdowns and fewer interceptions than Mahomes in a game opposite the two-time Super Bowl champion across his 127 starts in college and the NFL, according to OptaStats. This performance led to Cowboys All-Pro linebacker Micah Parsons to stand up for Wilson when retired NFL safety Rodney Harrison, a current NBC Sports analyst, put down the Jets third-year quarterback on national television after “Sunday Night Football.”

Between former Packers backup Tim Boyle and journeyman Trevor Siemian being the other options in the Jets quarterback room for now and the draft capital invested in Wilson, the BYU alum is the least likely to be tossed aside among the passers in jeopardy of losing their jobs.

There are several intriguing storylines heading into Week 5 of the 2023 NFL schedule, which only adds excitement to Week 5 NFL office pool picks. Justin Fields and the Chicago Bears are still searching for their first victory and will travel to the nation’s capital to play Sam Howell and the Washington Commanders on Thursday Night Football. Meanwhile, Jalen Hurts and the Philadelphia Eagles will try to start the season 5-0 with a victory over the Los Angeles Rams on the road.

The Eagles are 5-point favorites over the Rams in the Week 5 NFL odds according to the SportsLine Consensus. Will Philadelphia stay undefeated and cover the spread on the road, and which other teams should you target as you make your NFL confidence pool picks? Before you make your NFL predictions, you need to see the Week 5 NFL football pool picks from SportsLine’s proven computer model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 5 of the 2023 NFL season on an incredible 168-118 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 22-10 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has simulated the entire Week 5 NFL schedule 10,000 times and generated its optimal NFL pick’em plays. Head to SportsLine to see them now.

Top Week 5 NFL office pool predictions
One of the top Week 5 NFL predictions from the model: The Detroit Lions (-9) comfortably beat the Carolina Panthers at home. The Lions are coming off a convincing 34-20 victory over the Green Bay Packers last Thursday. Running back David Montgomery had a strong showing in Detroit’s win, rushing 32 times for 121 yards and three touchdowns.

The Lions will enter Sunday’s showdown averaging 26.5 points per game, which ranks eighth in the NFL. Quarterback Jared Goff is completing 69.5% of his passes for 1,029 yards and six touchdowns through the first four games this season.

The Panthers, meanwhile, have struggled mightily on the road, losing 12 of their last 14 away games. In addition, Carolina has lost four of its last five games against opponents from the NFC. SportsLine’s model expects Detroit’s offense to rack up over 350 total yards on Sunday, helping the Lions win outright in well over 70% of simulations. See the rest of the model’s Week 5 NFL pool picks here.

How to make Week 5 NFL office pool picks
The model also made the call on every other Week 5 NFL game and has strong picks for potentially close NFL matchups like Cowboys vs. 49ers, Saints vs. Patriots, and Packers vs. Raiders. It’s also calling for several favorites to struggle big-time. You can only see all of the model’s NFL pool picks here.

Teams looking to rebound from disappointing losses will kick off Week 5 of the 2023 NFL schedule when the Washington Commanders (2-2) host the Chicago Bears (0-4) on Thursday Night Football. Washington is coming off its second straight defeat, a 34-31 overtime setback at Philadelphia in which it owned a 10-point lead in the second quarter. Chicago saw its franchise-record losing streak reach 14 games after it dropped a 31-28 home decision to Denver after squandering a 21-point advantage in the second half.

Kickoff from FedExField in Landover, Md. is set for 8:15 p.m. ET. Washington is a 6.5-point favorite in the latest Bears vs. Commanders odds, while the over/under for total points scored is 44.5. Before making any Commanders vs. Bears picks, you need to see the NFL predictions and betting advice from SportsLine’s Advanced Computer Model.

The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 5 of the 2023 NFL season on an incredible 168-118 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 22-10 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Commanders vs. Bears and just locked in its picks and Thursday Night Football predictions. You can head to SportsLine now to see the model’s picks. Here are several NFL odds and betting lines for Bears vs. Commanders:

Bears vs. Commanders spread: Washington -6.5
Bears vs. Commanders over/under: 44.5 points
Bears vs. Commanders money line: Washington -300, Chicago +239
WAS: Commanders are 6-1 against the spread in their last seven meetings with Chicago
CHI: Bears are 1-8-1 ATS in their last 10 overall games
Bears vs. Commanders picks: See picks at SportsLine
Why the Commanders can cover
After getting manhandled by Buffalo in its previous game, Washington gave the undefeated Eagles all they could handle in Week 4. The Commanders, who managed just a final-minute field goal in their 37-3 loss to the Bills after scoring a total of 55 points over their first two games of the year, built a double-digit lead in the first half and erased a pair of deficits in the fourth quarter. The club forced overtime against Philadelphia when Sam Howell threw a 10-yard touchdown pass to Jahan Dotson on the final play of regulation.

The 23-year-old Howell racked up 290 passing yards without an interception against the defending NFC champions a week after registering only 170 yards and getting picked off four times against Buffalo. Brian Robinson Jr. rushed for 45 yards and his third TD of the season in the loss at Philadelphia after recording just two scoring runs as a rookie in 2022. See which team to pick here.

Why the Bears can cover
Chicago was on its way to its first victory since Week 7 of the 2022 campaign last Sunday after it possessed a 28-7 lead over the Broncos late in the third quarter before collapsing. The Bears outgained Denver 471-311 overall and 171-97 on the ground while having a 26-17 advantage in first downs. Khalil Herbert recorded his third career 100-yard rushing performance and first since Week 3 of last season, gaining 103 yards on 18 carries, and also hauled in a touchdown pass.

Justin Fields came up with a herculean effort against the Broncos, atoning for an outing against Kansas City the previous week in which he threw for only 99 yards. The 24-year-old quarterback completed his first 16 pass attempts, the longest streak at any point in a game in team history, before ending the first half with an incompletion on a Hail Mary. Fields finished with career-highs of 335 passing yards and four TD tosses, including two to tight end Cole Kmet. See which team to pick here.